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Heterogeneity of biological models While human clinical studies are available, the vast majority of studies aiming at investigating potential toxic effects of e-cigarettes use preclinical models such as cell culture and animal models [7]

Addiction and Withdrawal : Nicotine in cigarettes is highly addictive, leading to physical dependence and withdrawal symptoms when quitting smoking.

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Outcomes of sprayed cultured epithelial autografts for full-thickness wounds: a single-centre experience